Susan - We can assure you that there are no harmful chemicals in any of our mattresses. If you are highly sensitive to odors, then you may also be highly sensitive to the smell of a new mattress, which should dissipate within a day or two once the mattress is unpacked and set up in your home. We recommend airing out in the room, like you are doing, using open windows for fresh air. The smell should not be intense and should dissipate, but again if you are highly sensitive it may be a different experience for you. If you need further assistance, please email us at SertaCare at gmail dot com. Thanks!